shswkna an hour ago

From the article:

> They can also increase suicidal ideation.

A very close family member committed suicide, after Prozac dosage adjustments made his brain chemistry go haywire.

This happened 30 years ago, and it has been known to us that Prozac can cause this, since then.

The Guardians headline is way, way understating the real situation here.

  • carsoon 41 minutes ago

    The problem with suicidal depression is that if someone has created the thought pattern that death is best, then removing the symptoms of depression (lethargy, lack of energy, no willpower) now gives the person the ability to actually follow through with the act.

    Medications almost always target symptoms and never address root causes.

    • fragrom 19 minutes ago

      This is what my psychiatrist more or less warned me about when I went on medication; that a lot of people who are suicidal lack the energy and ability to plan their suicide, and medications can sometimes undo those particular symptoms and people manage to end themselves.

      I'm not sure what kinds of studies have been done about it, but I've had a few therapists same similar ideas. If it's not a studied phenomenon, then it has folks that believe it exists.

    • pixelready 18 minutes ago

      Finding everyone’s cow is expensive and time consuming: https://antidepressantcow.org/2020/02/the-story-of-the-antid...

      But is the only true cure to the suffering. We’d have to undergo a massive reorganization of society (and upset a few hefty profit margins) to prioritize that, so we settle for the messy symptom management we have.

      • an0malous a minute ago

        I don’t think everyone’s antidepressant cow is that different, modern life just sucks and the only ones who are happy are the people who still think they can win the rat race. People who are depressed just realize this and we medicate them not really for their benefit but because the whole system depends on productive, compliant workers.

        You’re right that the blocker is upsetting profit margins though.

    • kayodelycaon 20 minutes ago

      Yup. Depression medication can significantly help the emotional symptoms, but that takes longer to be effective.

      I’m bipolar and a lot of the medication I take does not become fully effective for months. For me, my medication slowly became more effective over years as my brain no longer had to compensate for hardware problems.

  • ekianjo 23 minutes ago

    Suicidal ideation is a risk for many CNS drugs, and not unique to Prozac as far as I know. But yes this is a major risk factor that needs to be taken in account before such kind of treatments.

marcus_holmes 32 minutes ago

> "But a new review of trial data by academics in Austria and the UK concluded that..."

> "Mark Horowitz, an associate professor of psychiatry at Adelaide University and a co-author of the study,"

Austria - cold, has mountains, but not Adelaide University

Australia - hot, has kangaroos, and Adelaide University

Is the Grauniad returning to form?

monero-xmr 19 minutes ago

SSRIs literally saved my life, no question about it. Night and day difference, from daily panic attacks destroying my life, happiness, and career, to being almost completely better in 2 weeks after starting. I tried exercise and diet and meditation and you name it, for years!, before I gave medication a go.

Do not care what the science says. It 100% worked for me. Please get help if you need it, tens of millions of people use this medicine successfully

Articles like this are part of the narrative that SSRIs in general are no better than placebo. Absolutely not true for me!

  • fgonzag 6 minutes ago

    Same here, after struggling for 39 years, glp-1 + SSRI + ADHD meds have made me a normal productive human, and 2 years ago I had pretty much given up on the possibility.

    Having a child forced me to fix my life, and I'm incredibly happy because of it.

    • ipnon 4 minutes ago

      Pharmacology and chemistry can really make the world a better place.

djohnston 19 minutes ago

It’s fascinating that otherwise intelligent people have no hesitation pumping their children’s developing brains full of SSRIs and amphetamines at the behest of a professional class who is paid to distribute these medications.